Maltese Cross Sign Fatty Casts
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Fatty casts are characteristic of degenerative tubular disease and are frequently associated with heavy proteinuria.
Maltese cross sign fatty casts. Round particles producing birefringent maltese crosses under polarized light are commonly seen in the urinary sediment of patients with a nephrotic syndrome. Although chiefly associated with the knights hospitaller order of st. A routine urinalysis demonstrates proteinuria and fatty casts. Formed by the breakdown of lipid rich epithelial cells these are hyaline casts with fat globule inclusions yellowish tan in color.
John now the. Renal failure casts wider than normal cast matrix. It is a heraldic cross variant which developed from earlier forms of eight pointed crosses in the 16th century. Nephrotic syndrome maltese cross sign.
Rbc casts in the urine. If cholesterol or cholesterol esters are present they are associated with the maltese cross sign under polarized light. Fatty casts with maltese cross sign. Fatty casts oval fat bodies nephrotic syndrome.
Average 5 0 of 7 ratings. Hypoalbuminemia hyperlipidemia and lipiduria. The maltese cross is a cross symbol consisting of four v or arrowhead shaped concave quadrilaterals converging at a central vertex at right angles two tips pointing outward symmetrically. Dm crush injuries nephrotic syndrome tubular necrosis.
Fatty degeneration of the tubular epithelium in degenerative tubular disease. The appearance of the maltese crosses is due to the birefringence of lipid droplets which consist mainly of cholesterol esters. This formation is indicated by the white arrow in the bottom image. Fatty casts with maltese cross sign.
Based on these findings the physician decided to proceed with a kidney biopsy. Fatty casts containing cholesterol will produce classic maltese cross formations under polarized light. Non specific please rate topic.